May 2020. The quarantined governor, a scientist, and a former model and streamer receive puzzle boxes containing invitations from their mutual friend, tech billionaire Miles Brone, to visit a mansion on a private Greek island and take part in a murder-mystery game centered on the host's murder. A similar invitation is received by private detective Benoit Blanc, who eagerly accepts the invitation. The motley group arriving in Greece is surprised and not particularly pleased by the appearance of Andi Brand — Miles's former business partner, with whom he founded the company. Tension mounts as a real murder occurs during the party.