In the mind of an ordinary 11-year-old schoolgirl named Riley live five basic emotions: Joy, Sadness, Fear, Anger, and Disgust. Each day they help the girl cope with problems, guiding all of her actions. Suddenly it turns out that Riley and her parents are about to move from a small cozy town to a noisy and crowded megacity. Each of the emotions believes that it alone knows best what needs to be done in this difficult situation, and in the girl's mind a total chaos ensues.