To keep his job at the zoo, David agrees to transport a certain cargo aboard a cruise liner. Seizing the opportunity, he invites his ex-wife and son on the trip, with whom he hopes to repair their relationship. But when David’s colleague accidentally opens the package, a charming Marsupilami—a red, fluffy creature—turns out to be what’s inside, and it is hunted by poachers around the world. After all, Marsupilami is not only a fan of dangerous antics, but also the key to eternal youth. The trip immediately descends into complete chaos.