Amber, along with four girlfriends, sets out from Los Angeles to Joshua Tree to spend the weekend and have fun. However, once they find themselves outside a large desert town, the girls encounter open hostility from the locals. Gradually, clashes with the residents become increasingly brutal, and disagreements begin to mount within the group, which reveal Amber's dark secrets from her past. The weekend getaway turns into a struggle for survival, intensified by a thirst for revenge.